American Airlines flight AA 4605: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Daily 11:13 New York LaGuardia (LGA) B 12:27 Boston Logan (BOS) B
AA 4605 Non-stop Embraer EMB 175 (E75) 1:14 Effective 2025-09-03 through 2025-11-01
Daily 11:14 Saint Louis (STL) 1 12:40 Chicago O'Hare (ORD) 3
AA 4605 Non-stop Embraer EMB 175 (E75) 1:26 Effective 2025-12-03 through 2025-12-17
Daily 11:18 Saint Louis (STL) 1 12:40 Chicago O'Hare (ORD) 3
AA 4605 Non-stop Embraer EMB 175 (E75) 1:22 Effective from 2026-02-12
Daily 13:00 Boston Logan (BOS) B 14:17 New York LaGuardia (LGA) B
AA 4605 Non-stop Embraer EMB 175 (E75) 1:17 Effective 2025-09-03 through 2025-11-01
Mon-Fri,Sun 14:44 New York LaGuardia (LGA) B 16:32 Roanoke (ROA)
AA 4605 Non-stop Embraer EMB 175 (E75) 1:48 Effective 2025-05-05 through 2025-06-04
Mon-Fri,Sun 14:45 New York LaGuardia (LGA) B 16:39 Roanoke (ROA)
AA 4605 Non-stop Embraer EMB 175 (E75) 1:54 Valid until 2025-05-04
Mon-Fri,Sun 17:03 Roanoke (ROA) 18:40 New York LaGuardia (LGA) B
AA 4605 Non-stop Embraer EMB 175 (E75) 1:37 Effective 2025-05-05 through 2025-06-04
Mon-Fri,Sun 17:10 Roanoke (ROA) 18:50 New York LaGuardia (LGA) B
AA 4605 Non-stop Embraer EMB 175 (E75) 1:40 Valid until 2025-05-04
Mon-Wed 18:59 New York LaGuardia (LGA) B 20:13 Portland (PWM)
AA 4605 Non-stop Embraer EMB 175 (E75) 1:14 Effective 2025-06-09 through 2025-07-02
Mon-Wed 18:59 New York LaGuardia (LGA) B 20:24 Portland (PWM)
AA 4605 Non-stop Embraer EMB 175 (E75) 1:25 Effective 2025-07-07 through 2025-08-05
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4605: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4605
11:13
New York LaGuardia (LGA) B

12:27
Boston Logan (BOS) B
Effective 2025-09-03 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:14, non-stop
Embraer EMB 175 (E75)
American Airlines AA4605
11:14
Saint Louis (STL) 1

12:40
Chicago O'Hare (ORD) 3
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:26, non-stop
Embraer EMB 175 (E75)
American Airlines AA4605
11:18
Saint Louis (STL) 1

12:40
Chicago O'Hare (ORD) 3
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:22, non-stop
Embraer EMB 175 (E75)
American Airlines AA4605
13:00
Boston Logan (BOS) B

14:17
New York LaGuardia (LGA) B
Effective 2025-09-03 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:17, non-stop
Embraer EMB 175 (E75)
American Airlines AA4605
14:44
New York LaGuardia (LGA) B

16:32
Roanoke (ROA)
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:48, non-stop
Embraer EMB 175 (E75)
American Airlines AA4605
14:45
New York LaGuardia (LGA) B

16:39
Roanoke (ROA)
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:54, non-stop
Embraer EMB 175 (E75)
American Airlines AA4605
17:03
Roanoke (ROA)

18:40
New York LaGuardia (LGA) B
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:37, non-stop
Embraer EMB 175 (E75)
American Airlines AA4605
17:10
Roanoke (ROA)

18:50
New York LaGuardia (LGA) B
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:40, non-stop
Embraer EMB 175 (E75)
American Airlines AA4605
18:59
New York LaGuardia (LGA) B

20:13
Portland (PWM)
Effective 2025-06-09 through 2025-07-02
Mon
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:14, non-stop
Embraer EMB 175 (E75)
American Airlines AA4605
18:59
New York LaGuardia (LGA) B

20:24
Portland (PWM)
Effective 2025-07-07 through 2025-08-05
Mon
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:25, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Boston Logan (BOS) - New York LaGuardia (LGA)
  • New York LaGuardia (LGA) - Portland (PWM)
  • Roanoke (ROA) - New York LaGuardia (LGA)
  • Saint Louis (STL) - Chicago O'Hare (ORD)
All American Airlines flights
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